| Boss | Level Cap | Location | Active Squad | Honour Points |
|---|---|---|---|---|
| Gym #1: Brock | 14 | Pewter Gym | ||
| Rival #1 | - | Cerulean City | ||
| Gym #2: Misty | 21 | Cerulean Gym | ||
| Gym #3: Lt. Surge | 24 | Vermilion Gym | ||
| Rival #2 | - | S.S. Anne | ||
| Gym #4: Erika | 29 | Celadon Gym | ||
| Boss Giovanni #1 | - | Rocket Hideout | ||
| Gym 5#: Koga | 43 | Fuchsia Gym | ||
| Rival #3 | - | Pokémon Tower | ||
| Gym #6: Sabrina | 43 | Saffron Gym | ||
| Boss Giovanni #2 | - | Silph Co. | ||
| Gym #7: Blaine | 47 | Cinnabar Gym | ||
| Rival #4 | - | Route 22 | ||
| Gym #8: Giovanni | 50 | Viridian Gym | ||
| Elite Four Lorelei | 56 (62) | Indigo Plateau | ||
| Elite Four Bruno | 58 (62) | Indigo Plateau | ||
| Elite Four Agatha | 60 (62) | Indigo Plateau | ||
| Elite Four Lance | 62 | Indigo Plateau | ||
| Champion | 65 | Indigo Plateau |