| Boss | Level Cap | Location | Active Squad | Honour Points |
|---|---|---|---|---|
| Gym 1#: Falkner | 9 | Violet Gym | ||
| Gym #2: Bugsy | 16 | Azalea Gym | ||
| Rival #1 | - | Azalea Town | ||
| Gym #3: Whitney | 20 | Goldenrod Gym | ||
| Gym #4: Morty | 25 | Ecruteak Gym | ||
| Rival #2 | - | Burned Tower | ||
| Gym #5: Chuck | 31 | Cianwood Gym | ||
| Gym #6: Jasmine | 35 | Olivine Gym | ||
| Gym #7: Pryce | 31 | Mahogany Gym | ||
| Boss Petrel | - | Team Rocket HQ | ||
| Boss Archer | - | Radio Tower | ||
| Gym #8: Clair | 40 | Blackthorn Gym | ||
| Rival #3 | - | Victory Road | ||
| Elite Four Will | 42 (47) | Indigo Plateau | ||
| Elite Four Koga | 44 (47) | Indigo Plateau | ||
| Elite Four Bruno | 46 (47) | Indigo Plateau | ||
| Elite Four Karen | 47 | Indigo Plateau | ||
| Champion Lance | 50 | Indigo Plateau | ||
| Gym #9: Lt. Surge | 46 | Vermilion Gym | ||
| Gym #10: Sabrina | 48 | Saffron Gym | ||
| Gym #11: Misty | 47 | Cerulean Gym | ||
| Gym #12: Erika | 46 | Celadon Gym | ||
| Gym #13: Janine | 39 | Fuchsia Gym | ||
| Gym #14: Brock | 44 | Pewter Gym | ||
| Gym #15: Blaine | 50 | Seafoam Islands Gym | ||
| Gym #16: Blue | 58 | Viridian Gym | ||
| Red | 81 | Mt. Silver |